Chapter 4 Diagnostic and Treatment Issues in Postamputation Pain After Landmine Injury
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چکیده
منابع مشابه
Postamputation pain: epidemiology, mechanisms, and treatment
Postamputation pain (PAP) is highly prevalent after limb amputation but remains an extremely challenging pain condition to treat. A large part of its intractability stems from the myriad pathophysiological mechanisms. A state-of-art understanding of the pathophysiologic basis underlying postamputation phenomena can be broadly categorized in terms of supraspinal, spinal, and peripheral mechanism...
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Vasectomy is a very common operation and has been accepted as a method of family planning by ≈ 42 million couples worldwide. While it is usually a well-tolerated and highly effective form of birth control, it has a risk of significant morbidity in ≈ 1% of patients [1]. One particularly troubling complication after vasectomy is chronic testicular pain, which has been defined as intermittent or c...
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and ( j , δj) ⊥ ( `, δ`) (4.1c) for all j 6= `. The lengths of the vectors yj , β, and δj , respectively, are nj , r, and s. Like in all regression-type models, the explanatory variables X and Z are regarded as fixed variables, which can also be expressed by saying that the distributions of the random variables and δ are conditional onX andZ. The random variables and δ are also called the vecto...
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Reactive oxygen species (ROS) contribute to sensitization of pain pathways during neuropathic pain, but little is known about the primary sources of ROS production and how ROS mediate pain sensitization. Here, we show that the NADPH oxidase isoform Nox4, a major ROS source in somatic cells, is expressed in a subset of nonpeptidergic nociceptors and myelinated dorsal root ganglia neurons. Mice l...
متن کاملPostamputation pain and sensory changes in treatment-naive patients: characteristics and responses to treatment with tramadol, amitriptyline, and placebo.
BACKGROUND Pain after amputation is common but difficult to treat, and few controlled treatment studies exist. METHODS In the current study, 94 treatment-naive posttraumatic limb amputees with phantom pain (intensity: mean visual analog scale score [0-100], 40 [95% confidence interval, 38-41]) were randomly assigned to receive individually titrated doses of tramadol, placebo (double-blind com...
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ژورنال
عنوان ژورنال: Pain Medicine
سال: 2006
ISSN: 1526-2375,1526-4637
DOI: 10.1111/j.1526-4637.2006.00234_6.x